Please use this identifier to cite or link to this item: https://physrep.ff.bg.ac.rs/handle/123456789/1302
Title: Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity
Authors: Kop, Tatjana J.
Jakovljević, Dragica M.
Živković, Ljiljana S.
Žekić, Andrijana 
Beškoski, Vladimir P.
Milić, Dragana R.
Gojgić-Cvijović, Gordana D.
Bjelaković, Mira S.
Keywords: Antioxidant activity;Cholesterol-levan conjugate;DLS;Hydrophobized polysaccharides;Polysaccharide-C nanoparticles 60;SEM
Issue Date: 15-Jan-2020
Journal: European Polymer Journal
Abstract: 
An efficient encapsulation of the fullerene into two hydrophobized and one native polysaccharide provided water soluble supramolecular hybrids. After covalent modification of polysaccharides by cholesterol, noncovalent hybrids were prepared by a three-step procedure, including mixing of individual aqueous solutions of hydrophobized, as well as native sugar with solution of the fullerene in pyridine, dialysis and lyophilization. Although the degree of the fullerene incorporation into hydrophobized substrates, cholesterol-levan and cholesterol-pullulan, was lower in comparison to the native polysaccharide levan, hydrophobization provided nanoparticles with improved properties. The particle size distribution, studied by dynamic light scattering and scanning electron microscopy revealed formation of moderately polydisperse aggregates, with the diameter contraction in comparison to the corresponding free polysaccharide, especially in the case of hydrophobized substrates. The morphological examination, done by scanning electron microscopy indicated the self-organization of the fullerene-native polysaccharide to round individual structures, while fullerene-hydrophobized polysaccharide hybrids tend to form networks. The antioxidant activity of the synthesized polysaccharide-C60 noncovalent hybrids versus starting polysaccharides was investigated by the DPPH radical scavenging and the β-carotene-linoleic acid bleaching methods. In all three complexes, the radical scavenging ability of the fullerene remained preserved, and a positive effect of levan hydrophobization was observed.
URI: https://physrep.ff.bg.ac.rs/handle/123456789/1302
ISSN: 0014-3057
DOI: 10.1016/j.eurpolymj.2019.109461
Appears in Collections:Journal Article

Show full item record

SCOPUSTM   
Citations

14
checked on Dec 21, 2024

Page view(s)

46
checked on Dec 23, 2024

Google ScholarTM

Check

Altmetric

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.